An Ant-Based Model for Multiple Sequence Alignment
Identifieur interne : 000A56 ( France/Analysis ); précédent : 000A55; suivant : 000A57An Ant-Based Model for Multiple Sequence Alignment
Auteurs : Frédéric Guinand [France] ; Yoann Pigné [France]Source :
- Lecture Notes in Computer Science [ 0302-9743 ] ; 2008.
Abstract
Abstract: Multiple sequence alignment is a key process in today’s biology, and finding a relevant alignment of several sequences is much more challenging than just optimizing some improbable evaluation functions. Our approach for addressing multiple sequence alignment focuses on the building of structures in a new graph model: the factor graph model. This model relies on block-based formulation of the original problem, formulation that seems to be one of the most suitable ways for capturing evolutionary aspects of alignment. The structures are implicitly built by a colony of ants laying down pheromones in the factor graphs, according to relations between blocks belonging to the different sequences.
Url:
DOI: 10.1007/978-3-540-78827-0_63
Affiliations:
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<front><div type="abstract" xml:lang="en">Abstract: Multiple sequence alignment is a key process in today’s biology, and finding a relevant alignment of several sequences is much more challenging than just optimizing some improbable evaluation functions. Our approach for addressing multiple sequence alignment focuses on the building of structures in a new graph model: the factor graph model. This model relies on block-based formulation of the original problem, formulation that seems to be one of the most suitable ways for capturing evolutionary aspects of alignment. The structures are implicitly built by a colony of ants laying down pheromones in the factor graphs, according to relations between blocks belonging to the different sequences.</div>
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